Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is Not Altered in Response to Specific Silencing

ABSTRACT African trypanosomes evade the immune system of the mammalian host by the antigenic variation of the predominant glycosylphosphatidylinositol (GPI)-anchored surface protein, variant surface glycoprotein (VSG). VSG is a very stable protein that is turned over from the cell surface with a lon...

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Bibliographic Details
Main Authors: Mohamed Sharif, Paige Garrison, Peter Bush, James D. Bangs
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00122-22