An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission

An intranasal live-attenuated SARS-CoV-2 vaccine limits virus transmission

Abstract The development of effective SARS-CoV-2 vaccines has been essential to control COVID-19, but significant challenges remain. One problem is intramuscular administration, which does not induce robust mucosal immune responses in the upper airways—the primary site of infection and virus sheddin...

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Bibliographic Details
Main Authors: Julia M. Adler, Ricardo Martin Vidal, Christine Langner, Daria Vladimirova, Azza Abdelgawad, Daniela Kunecova, Xiaoyuan Lin, Geraldine Nouailles, Anne Voss, Sandra Kunder, Achim D. Gruber, Haibo Wu, Nikolaus Osterrieder, Dusan Kunec, Jakob Trimpert
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45348-2

Internet

https://doi.org/10.1038/s41467-024-45348-2

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