Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

Nuclear pore complexes (NPCs) conduct massive transport mediated by shuttling nuclear transport receptors (NTRs), while keeping nuclear and cytoplasmic contents separated. The NPC barrier in Xenopus relies primarily on the intrinsically disordered FG domain of Nup98. We now observed that Nup98 FG do...

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Bibliographic Details
Main Authors: Hermann Broder Schmidt, Dirk Görlich
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
Tetrahymena
importin
nucleoporin
nucleocytoplasmic transport
Nup100
Nup116
Online Access:https://elifesciences.org/articles/04251

Internet

https://elifesciences.org/articles/04251

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