Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch

C-di-GMP, a cyclic guanine dinucleotide, has been shown to regulate biofilm formation as well as virulence gene expression in a variety of bacteria. Analogues of c-di-GMP have the potential to be used as chemical probes to study c-di-GMP signaling and could even become drug leads for the development...

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Bibliographic Details
Main Authors: Herman O. Sintim, Nirmal Pahadi, Jingxin Wang, David A. Sayre, Jie Zhou
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/11/13376