Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.

Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease.

BACKGROUND: Prion diseases are a group of invariably fatal neurodegenerative disorders affecting humans and a wide range of mammals. An essential part of the infectious agent, termed the prion, is composed of an abnormal isoform (PrPSc) of a host-encoded normal cellular protein (PrPC). The conversio...

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Bibliographic Details
Main Authors: Gaby Schoch, Harald Seeger, Julien Bogousslavsky, Markus Tolnay, Robert Charles Janzer, Adriano Aguzzi, Markus Glatzel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-02-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1316067?pdf=render

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http://europepmc.org/articles/PMC1316067?pdf=render

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