Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes

Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes

Plasmodium ookinetes use an invasive apparatus to invade mosquito midguts, and tubulins are the major structural proteins of this apical complex. We examined the role of tubulins in malaria transmission to mosquitoes. Our results demonstrate that the rabbit polyclonal antibodies (pAb) against human...

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Bibliographic Details
Main Authors: Genwei Zhang, Guodong Niu, Diana Hooker–Romera, Sadeq Shabani, Julian Ramelow, Xiaohong Wang, Noah S. Butler, Anthony A. James, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
mosquito
pathogen-host interaction
ookinete
invasive apparatus
malaria transmission-blocking vaccine
FREP1
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1132647/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1132647/full

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