Immunomodulatory Microparticles Epigenetically Modulate T Cells and Systemically Ameliorate Autoimmune Arthritis

Immunomodulatory Microparticles Epigenetically Modulate T Cells and Systemically Ameliorate Autoimmune Arthritis

Abstract Disease modifying antirheumatic drugs (DMARDs) have improved the prognosis of autoimmune inflammatory arthritides but a large fraction of patients display partial or nonresponsiveness to front‐line DMARDs. Here, an immunoregulatory approach based on sustained joint‐localized release of all‐...

Full description

Bibliographic Details
Main Authors: David A. McBride, Matthew D. Kerr, Wade T. Johnson, Anders Nguyen, Martina Zoccheddu, Mina Yao, Edward B. Prideaux, Nicholas C. Dorn, Wei Wang, Mattias N.D. Svensson, Nunzio Bottini, Nisarg J. Shah
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Advanced Science
Subjects:
immune engineering
regulatory T cells
rheumatoid arthritis
Online Access:https://doi.org/10.1002/advs.202202720

Internet

https://doi.org/10.1002/advs.202202720

Similar Items