The “myth” of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?

The “myth” of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?

Abstract Systemic sclerosis is considered a disease dominated by a “loss of angiogenesis”, although in its early phases evidence indicates a disturbed angiogenic response only. In fact, microvascular changes are primarily due to endothelial cell injury, triggering downstream significant enlargement...

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Bibliographic Details
Main Authors: Marco Matucci-Cerinic, Mirko Manetti, Cosimo Bruni, Ines Chora, Silvia Bellando-Randone, Gemma Lepri, Amato De Paulis, Serena Guiducci
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Arthritis Research & Therapy
Subjects:
Scleroderma
Systemic sclerosis
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s13075-017-1370-5

Internet

http://link.springer.com/article/10.1186/s13075-017-1370-5

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