The “myth” of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?
Abstract Systemic sclerosis is considered a disease dominated by a “loss of angiogenesis”, although in its early phases evidence indicates a disturbed angiogenic response only. In fact, microvascular changes are primarily due to endothelial cell injury, triggering downstream significant enlargement...
Main Authors: | Marco Matucci-Cerinic, Mirko Manetti, Cosimo Bruni, Ines Chora, Silvia Bellando-Randone, Gemma Lepri, Amato De Paulis, Serena Guiducci |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-07-01
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Series: | Arthritis Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13075-017-1370-5 |
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