In Vitro Studies of Lipopolysaccharide-Mediated DNA Release of Podovirus HK620

Gram-negative bacteria protect themselves with an outermost layer containing lipopolysaccharide (LPS). O-antigen-specific bacteriophages use tailspike proteins (TSP) to recognize and cleave the O-polysaccharide part of LPS. However, O-antigen composition and structure can be highly variable dependin...

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Bibliographic Details
Main Authors: Nina K. Broeker, Franziska Kiele, Sherwood R. Casjens, Eddie B. Gilcrease, Anja Thalhammer, Joachim Koetz, Stefanie Barbirz
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/10/6/289