Bi-directional neuro-immune dysfunction after chronic experimental brain injury

Bi-directional neuro-immune dysfunction after chronic experimental brain injury

Abstract Background It is well established that traumatic brain injury (TBI) causes acute and chronic alterations in systemic immune function and that systemic immune changes contribute to posttraumatic neuroinflammation and neurodegeneration. However, how TBI affects bone marrow (BM) hematopoietic...

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Bibliographic Details
Main Authors: Rodney M. Ritzel, Yun Li, Yun Jiao, Sarah J. Doran, Niaz Khan, Rebecca J. Henry, Kavitha Brunner, David J. Loane, Alan I. Faden, Gregory L. Szeto, Junfang Wu
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Neuroinflammation
Subjects:
Traumatic brain injury
Bone marrow transplantation
Long-term reconstitution
Hematopoiesis
Innate immunity
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-024-03082-y

Internet

https://doi.org/10.1186/s12974-024-03082-y

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