A consortia of clinical E. coli strains with distinct in vitro adherent/invasive properties establish their own co-colonization niche and shape the intestinal microbiota in inflammation-susceptible mice

Abstract Background Inflammatory bowel disease (IBD) patients experience recurrent episodes of intestinal inflammation and often follow an unpredictable disease course. Mucosal colonization with adherent-invasive Escherichia coli (AIEC) are believed to perpetuate intestinal inflammation. However, it...

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Bibliographic Details
Main Authors: Rachel M. Bleich, Chuang Li, Shan Sun, Ju-Hyun Ahn, Belgin Dogan, Cassandra J. Barlogio, Christopher A. Broberg, Adrienne R. Franks, Emily Bulik-Sullivan, Ian M. Carroll, Kenneth W. Simpson, Anthony A. Fodor, Janelle C. Arthur
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Microbiome
Subjects:
Online Access:https://doi.org/10.1186/s40168-023-01710-y