Peripheral blood T cell dynamics predict relapse in multiple sclerosis patients on fingolimod.

Peripheral blood T cell dynamics predict relapse in multiple sclerosis patients on fingolimod.

Fingolimod efficiently reduces multiple sclerosis (MS) relapse by inhibiting lymphocyte egress from lymph nodes through down-modulation of sphingosine 1-phosphate (S1P) receptors. We aimed to clarify the alterations in peripheral blood T cell subsets associated with MS relapse on fingolimod.Blood sa...

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Bibliographic Details
Main Authors: Zi-Ye Song, Ryo Yamasaki, Yuji Kawano, Shinya Sato, Katsuhisa Masaki, Satoshi Yoshimura, Dai Matsuse, Hiroyuki Murai, Takuya Matsushita, Jun-ichi Kira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4412716?pdf=render

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http://europepmc.org/articles/PMC4412716?pdf=render

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