The Prevention of Ischemia-Reperfusion Injury in Elderly Rats after Lower Limb Tourniquet Use

The Prevention of Ischemia-Reperfusion Injury in Elderly Rats after Lower Limb Tourniquet Use

Background: Lower limb ischemia-reperfusion injury (IRI-LL) is a common major complication of orthopedic surgery, especially in elderly patients. It has previously been demonstrated that folinic acid (FA) reduced IRI-LL damage in 3–4-month-old rats. This current work analyses the effect of FA in the...

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Bibliographic Details
Main Authors: Borja Herrero de la Parte, Javier Roa-Esparza, Iñigo Cearra, Inmaculada Ruiz Montesinos, Daniel Alonso-Alconada, Ana Alonso-Varona, Carmen Mar Medina, Sira Iturrizaga Correcher, Ignacio García-Alonso
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
ischemia-reperfusion injury
lower limb
elderly rats
prophylactic treatment
folinic acid
functional recovery
Online Access:https://www.mdpi.com/2076-3921/11/10/1936

Internet

https://www.mdpi.com/2076-3921/11/10/1936

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