Isolated growth hormone deficiency in children with vertically transmitted short stature: What do the genes tell us?

Isolated growth hormone deficiency in children with vertically transmitted short stature: What do the genes tell us?

IntroductionThe growth hormone deficiency (GHD) diagnosis is controversial especially due to low specificity of growth hormone (GH) stimulation tests. It is therefore believed that children diagnosed with GHD form a heterogeneous group with growth disorder frequently independent on GH function. No s...

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Bibliographic Details
Main Authors: Lukas Plachy, Shenali Anne Amaratunga, Petra Dusatkova, Klara Maratova, Vit Neuman, Lenka Petruzelkova, Dana Zemkova, Barbora Obermannova, Marta Snajderova, Stanislava Kolouskova, Zdenek Sumnik, Jan Lebl, Stepanka Pruhova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
short stature
growth hormone
growth hormone deficiency
genetics
next-generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1102968/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1102968/full

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