The Blocking of Integrin-Mediated Interactions with Maternal Endothelial Cells Reversed the Endothelial Cell Dysfunction Induced by EVs, Derived from Preeclamptic Placentae

The Blocking of Integrin-Mediated Interactions with Maternal Endothelial Cells Reversed the Endothelial Cell Dysfunction Induced by EVs, Derived from Preeclamptic Placentae

Placental extracellular vesicles (EVs) have increasingly been recognized as a major mediator of feto-maternal communication. However, the cellular and molecular mechanisms of the uptake of placental EVs by recipient cells are still not well-understood. We previously reported that placental EVs targe...

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Bibliographic Details
Main Authors: Yourong Feng, Qi Chen, Sien Yee Lau, Bridget W. Tsai, Katie Groom, Carolyn J. Barrett, Lawrence W. Chamley
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicle
placenta
preeclampsia
microparticle
integrin
Online Access:https://www.mdpi.com/1422-0067/23/21/13115

Internet

https://www.mdpi.com/1422-0067/23/21/13115

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