Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler

Comparing tuberculosis gene signatures in malnourished individuals using the TBSignatureProfiler

Abstract Background Gene expression signatures have been used as biomarkers of tuberculosis (TB) risk and outcomes. Platforms are needed to simplify access to these signatures and determine their validity in the setting of comorbidities. We developed a computational profiling platform of TB signatur...

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Bibliographic Details
Main Authors: W. Evan Johnson, Aubrey Odom, Chelsie Cintron, Mutharaj Muthaiah, Selby Knudsen, Noyal Joseph, Senbagavalli Babu, Subitha Lakshminarayanan, David F. Jenkins, Yue Zhao, Ethel Nankya, C. Robert Horsburgh, Gautam Roy, Jerrold Ellner, Sonali Sarkar, Padmini Salgame, Natasha S. Hochberg
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
RNA-sequencing
Gene sets
Signatures
Biomarkers
Latent tuberculosis infection
Online Access:https://doi.org/10.1186/s12879-020-05598-z

Internet

https://doi.org/10.1186/s12879-020-05598-z

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