RNA polymerase I promoter and splice acceptor site recognition affect gene expression in non-pathogenic Leishmania species

RNA polymerase I promoter and splice acceptor site recognition affect gene expression in non-pathogenic Leishmania species

Leishmania (Sauroleishmania) tarentolae has biotechnological potential for use as live vaccine against visceral leishmaniasis and as a system for the over expression of eukaryotic proteins that possess accurate post-translational modifications. For both purposes, new systems for protein expression i...

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Bibliographic Details
Main Authors: Tereza Cristina Orlando, Mário Gustavo Mayer, David A Campbell, Nancy R Sturm, Lucile Maria Floeter-Winter
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2007-11-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
intergenic spacer
heterologous protein system
polypyrimidine tract
trans-splicing acceptor site
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000700019

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000700019

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