The senescence-associated secretory phenotype as a driver of tumor growth: does G3BP1 hold the key?

Cellular senescence is a double-edged sword that, depending on the context, acts as either a potent tumor protective mechanism or an age-related driver of diseases such as cancer. Our recent findings show that the rasGAP SH3-binding protein 1 (G3BP1) activates the senescent-associated secretory phen...

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Bibliographic Details
Main Authors: Amr Omer, Sergio Di Marco, Imed-Eddine Gallouzi
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2020.1850161