A <i>Villin</i>-Driven <i>Fxr</i> Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an <i>n</i>-6-Enriched High-Fat Diet

A <i>Villin</i>-Driven <i>Fxr</i> Transgene Modulates Enterohepatic Bile Acid Homeostasis and Response to an <i>n</i>-6-Enriched High-Fat Diet

A diet high in <i>n</i>-6 polyunsaturated fatty acids (PUFAs) may contribute to inflammation and tissue damage associated with obesity and pathologies of the colon and liver. One contributing factor may be dysregulation by <i>n</i>-6 fatty acids of enterohepatic bile acid (BA...

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Bibliographic Details
Main Authors: Spencer N. Wren, Micah G. Donovan, Ornella I. Selmin, Tom C. Doetschman, Donato F. Romagnolo
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
farnesoid X receptor
bile acids
high-fat diet
soybean oil
<i>n</i>-6
linoleic acid
Online Access:https://www.mdpi.com/1422-0067/21/21/7829

Internet

https://www.mdpi.com/1422-0067/21/21/7829

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