Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

Kinesin Kip2 enhances microtubule growth in vitro through length-dependent feedback on polymerization and catastrophe

The size and position of mitotic spindles is determined by the lengths of their constituent microtubules. Regulation of microtubule length requires feedback to set the balance between growth and shrinkage. Whereas negative feedback mechanisms for microtubule length control, based on depolymerizing k...

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Bibliographic Details
Main Authors: Anneke Hibbel, Aliona Bogdanova, Mohammed Mahamdeh, Anita Jannasch, Marko Storch, Erik Schäffer, Dimitris Liakopoulos, Jonathon Howard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
microtubule dynamics
motor protein
length regulation
positive feedback
Online Access:https://elifesciences.org/articles/10542

Internet

https://elifesciences.org/articles/10542

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