How Clustered DNA Damage Can Change the Electronic Properties of ds-DNA—Differences between GAG, GA<sup>OXO</sup>G, and <sup>OXO</sup>GA<sup>OXO</sup>G

How Clustered DNA Damage Can Change the Electronic Properties of ds-DNA—Differences between GAG, GA<sup>OXO</sup>G, and <sup>OXO</sup>GA<sup>OXO</sup>G

Every 24 h, roughly 3 × 10<sup>17</sup> incidences of DNA damage are generated in the human body as a result of intra- or extra-cellular factors. The structure of the formed lesions is identical to that formed during radio- or chemotherapy. Increases in the clustered DNA damage (CDL) lev...

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Bibliographic Details
Main Author: Boleslaw Karwowski
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomolecules
Subjects:
Base Excision Repair
7,8-dihydro-8-oxo-2′-deoxyguanosine
electron hole and excess electron transfer
reactive oxygen species
electronic properties
DFT
Online Access:https://www.mdpi.com/2218-273X/13/3/517

Internet

https://www.mdpi.com/2218-273X/13/3/517

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