Is cumulative frequency of mitochondrial DNA variants a biomarker for colorectal tumor progression?

<p>Abstract</p> <p>To examine the relationship between mitochondrial DNA (mtDNA) alterations and colorectal tumorigenesis, we used high-resolution restriction endonucleases and sequencing to assess the mitochondrial genome from three histologic subtypes of colorectal adenomas (tubu...

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Bibliographic Details
Main Authors: Okoli Joel, Carey Delicia, Khan Masood, Aikhionbare Felix O, Go Rodney
Format: Article
Language:English
Published: BMC 2004-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/3/1/30