Allopurinol Suppresses Azoxymethane-Induced Colorectal Tumorigenesis in C57BL/KsJ-<i>db</i>/<i>db</i> Mice

Allopurinol Suppresses Azoxymethane-Induced Colorectal Tumorigenesis in C57BL/KsJ-<i>db</i>/<i>db</i> Mice

Obesity and related metabolic disorders, including chronic inflammation and enhanced oxidative stress, are closely associated with the development and progression of colorectal cancer. Previous epidemiological studies have demonstrated that increased serum uric acid is associated with the risk for v...

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Bibliographic Details
Main Authors: Junichi Kato, Yohei Shirakami, Kimihiro Yamaguchi, Taku Mizutani, Takayasu Ideta, Hiroshi Nakamura, Soranobu Ninomiya, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Takuji Tanaka, Masahito Shimizu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Gastrointestinal Disorders
Subjects:
allopurinol
uric acid
colorectal cancer
chemoprevention
obesity
oxidative stress
Online Access:https://www.mdpi.com/2624-5647/2/4/35

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https://www.mdpi.com/2624-5647/2/4/35

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