PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury

PRL2 regulates neutrophil extracellular trap formation which contributes to severe malaria and acute lung injury

Abstract Excessive host immune responses contribute to severe malaria with high mortality. Here, we show that PRL2 in innate immune cells is highly related to experimental malaria disease progression, especially the development of murine severe malaria. In the absence of PRL2 in myeloid cells, Plasm...

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Bibliographic Details
Main Authors: Xinyue Du, Baiyang Ren, Chang Li, Qi Li, Shuo Kan, Xin Wang, Wenjuan Bai, Chenyun Wu, Kokouvi Kassegne, Huibo Yan, Xiaoyin Niu, Min Yan, Wenyue Xu, Samuel C. Wassmer, Jing Wang, Guangjie Chen, Zhaojun Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45210-5

Internet

https://doi.org/10.1038/s41467-024-45210-5

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