Correlation between PARP-1 immunoreactivity and cytomorphological features of parthanatos, a specific cellular death in breast cancer cells

In parthanatos, a PARP-1 (poly (ADP-ribose) polymerase 1)-mediated cell death, dissipation of mitochondrial membrane potential, large-scale DNA fragmentation and chromatin condensation were observed. In contrast to apoptosis, it does not cause apoptotic bodies formation. Although PARP-1-mediated cel...

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Bibliographic Details
Main Authors: P. Donizy, A. Halon, P. Surowiak, G. Pietrzyk, C. Kozyra, R. Matkowski
Format: Article
Language:English
Published: PAGEPress Publications 2013-11-01
Series:European Journal of Histochemistry
Subjects:
Online Access:http://www.ejh.it/index.php/ejh/article/view/2224