The Safety and Efficacy of Nusinersen in the Treatment of Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The Safety and Efficacy of Nusinersen in the Treatment of Spinal Muscular Atrophy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

<i>Background and objectives</i>: Spinal muscular atrophy (SMA) is a neurodegenerative disease that leads to progressive proximal muscle weakness and muscle atrophy. To assess the beneficial and adverse effects of nusinersen, a promising intervention for SMA, we conducted a systematic se...

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Bibliographic Details
Main Authors: Kirellos Said Abbas, Mennatullah Mohamed Eltaras, Nahla Ahmed El-Shahat, Basel Abdelazeem, Mahmoud Shaqfeh, James Robert Brašić
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Medicina
Subjects:
adverse and beneficial effects
alpha motor neuron
bias
brainstem
evidence
neurodegenerative
Online Access:https://www.mdpi.com/1648-9144/58/2/213

Internet

https://www.mdpi.com/1648-9144/58/2/213

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