Is thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?

The DNA mismatch repair (MMR) system plays a crucial role in the prevention of replication errors and in the correction of some oxidative damages of DNA bases. In the present work the most abundant oxidized pyrimidine lesion, 5,6-dihydro-5,6-dihydroxythymidine (thymidine glycol, Tg) was tested for b...

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Bibliographic Details
Main Authors: Svetlana A Perevozchikova, Roman M Trikin, Roger J Heinze, Elena A Romanova, Tatiana S Oretskaya, Peter Friedhoff, Elena A Kubareva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136841?pdf=render