Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Abstract Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion is not clear. Toll-like receptors (TL...

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Bibliographic Details
Main Authors: Kai Ning Ma, Yao Zhang, Zhao Yu Zhang, Bo Ning Wang, Yan Yan Song, Lu Lu Han, Xin Zhuo Zhang, Shao Rong Long, Jing Cui, Zhong Quan Wang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Veterinary Research
Subjects:
Trichinella spiralis
galectin
Toll-like receptor 4 (TLR-4)
gut epithelium
invasion
MAPK-NF-κB pathway
Online Access:https://doi.org/10.1186/s13567-023-01246-x

Internet

https://doi.org/10.1186/s13567-023-01246-x

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