Nickel and aluminium mixture elicit memory impairment by activation of oxidative stress, COX-2, and diminution of AChE, BDNF and NGF levels in cerebral cortex and hippocampus of male albino rats

This study evaluated nickel and aluminium-induced neurotoxicity, as a binary metal mixture. Twenty-eight male Sprague Dawley albino rats were weight-matched and divided into four groups. Group 1 (control) received deionized water. Group 2 and 3 received Aluminium (1 mg/kg) and Nickel (0.2 mg/kg) res...

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Bibliographic Details
Main Authors: Chidinma P. Anyachor, Chinna N. Orish, Anthonet N. Ezejiofor, Ana Cirovic, Aleksandar Cirovic, Kenneth M. Ezealisiji, Orish E. Orisakwe
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Toxicology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666027X23000270