Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis

Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis

An important hallmark of radiation dermatitis is the impairment of the mitotic ability of the stem/progenitor cells in the basal cell layers due to radiation-induced DNA damage, leading to suppressed cell renewal in the epidermis. However, this mechanism alone does not adequately explain the complex...

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Bibliographic Details
Main Authors: Claudia E. Rübe, Benjamin M. Freyter, Gargi Tewary, Klaus Roemer, Markus Hecht, Christian Rübe
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
radiation dermatitis
ionizing radiation
skin inflammation
epidermis
cellular senescence
senescence-associated secretory phenotype (SASP)
Online Access:https://www.mdpi.com/1422-0067/25/6/3320

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https://www.mdpi.com/1422-0067/25/6/3320

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