A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver

Obesity is frequently associated with excessive accumulation of lipids in ectopic tissue and presents a major risk factor for type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). Diacylglycerols (DAGs) and ceramides (CERs) were identified as key players in lipid-induced insulin resis...

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Bibliographic Details
Main Authors: Christina Preuss, Tomas Jelenik, Kálmán Bódis, Karsten Müssig, Volker Burkart, Julia Szendroedi, Michael Roden, Daniel F. Markgraf
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/3/277