Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

Simvastatin to reduce pulmonary dysfunction in patients with acute respiratory distress syndrome: the HARP-2 RCT

Background: Acute lung injury is a common devastating clinical syndrome characterised by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure, and is a major cause of morbidity and mortality. Objective: This study tested the hypothesis that treatment with...

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Bibliographic Details
Main Authors: Daniel F McAuley, John G Laffey, Cecilia M O’Kane, Gavin D Perkins, Brian Mullan, Thomas J Trinder, Paul Johnston, Phillip A Hopkins, Andrew J Johnston, Lynn Murphy, Christine McNally, Ashley M Agus, Clíona McDowell, Colette Jackson
Format: Article
Language:English
Published: NIHR Journals Library 2018-01-01
Series:Efficacy and Mechanism Evaluation
Subjects:
acute respiratory distress syndrome
ards
statins
mechanical ventilation
ventilator-free days
critical care
intensive care unit
Online Access:https://doi.org/10.3310/eme05010

Internet

https://doi.org/10.3310/eme05010

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