Paradoxical pharmacological dissociations result from drugs that enhance delta oscillations but preserve consciousness

Abstract Low-frequency (<4 Hz) neural activity, particularly in the delta band, is generally indicative of loss of consciousness and cortical down states, particularly when it is diffuse and high amplitude. Remarkably, however, drug challenge studies of several diverse classes of pharmacological...

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Bibliographic Details
Main Authors: Joel Frohlich, Pedro A. M. Mediano, Francesco Bavato, Alireza Gharabaghi
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04988-8