Monte Carlo Method and GA-MLR-Based QSAR Modeling of NS5A Inhibitors against the Hepatitis C Virus

Monte Carlo Method and GA-MLR-Based QSAR Modeling of NS5A Inhibitors against the Hepatitis C Virus

Hepatitis C virus (HCV) is a serious disease that threatens human health. Despite consistent efforts to inhibit the virus, it has infected more than 58 million people, with 300,000 deaths per year. The HCV nonstructural protein NS5A plays a critical role in the viral life cycle, as it is a major con...

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Bibliographic Details
Main Authors: Wissal Liman, Mehdi Oubahmane, Ismail Hdoufane, Imane Bjij, Didier Villemin, Rachid Daoud, Driss Cherqaoui, Achraf El Allali
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
chemoinformatics
drug discovery
molecular descriptors
QSAR
HCV
NS5A
Online Access:https://www.mdpi.com/1420-3049/27/9/2729

Internet

https://www.mdpi.com/1420-3049/27/9/2729

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