In vitro and in silico studies of 7′′,8′′-buddlenol D anti-inflammatory lignans from Carallia brachiata as p38 MAP kinase inhibitors

Abstract Excessive macrophage activation induces the release of high levels of inflammatory mediators which not only amplify chronic inflammation and degenerative diseases but also exacerbate fever and retard wound healing. To identify anti-inflammatory molecules, we examined Carallia brachiata—a me...

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Bibliographic Details
Main Authors: Nonthaneth Nalinratana, Utid Suriya, Chanyanuch Laprasert, Nakuntwalai Wisidsri, Preeyaporn Poldorn, Thanyada Rungrotmongkol, Wacharee Limpanasitthikul, Ho-Cheng Wu, Hsun-Shuo Chang, Chaisak Chansriniyom
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-30475-5