Reconstruction of the Genome-Scale Metabolic Model of <i>Saccharopolyspora erythraea</i> and Its Application in the Overproduction of Erythromycin

<i>Saccharopolyspora erythraea</i> is considered to be an effective host for erythromycin. However, little is known about the regulation in terms of its metabolism. To develop an accurate model-driven strategy for the efficient production of erythromycin, a genome-scale metabolic model (...

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Bibliographic Details
Main Authors: Feng Xu, Ju Lu, Xiang Ke, Minghao Shao, Mingzhi Huang, Ju Chu
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/6/509