Transcription pausing regulates mouse embryonic stem cell differentiation
The pluripotency of embryonic stem cells (ESCs) relies on appropriate responsiveness to developmental cues. Promoter-proximal pausing of RNA polymerase II (Pol II) has been suggested to play a role in keeping genes poised for future activation. To identify the role of Pol II pausing in regulating ES...
| Autors principals: | , , , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
Elsevier
2017-12-01
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| Col·lecció: | Stem Cell Research |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S1873506117302428 |