Circular RNA repertoires are associated with evolutionarily young transposable elements

Circular RNAs (circRNAs) are found across eukaryotes and can function in post-transcriptional gene regulation. Their biogenesis through a circle-forming backsplicing reaction is facilitated by reverse-complementary repetitive sequences promoting pre-mRNA folding. Orthologous genes from which circRNA...

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Bibliographic Details
Main Authors: Franziska Gruhl, Peggy Janich, Henrik Kaessmann, David Gatfield
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/67991