Computational analysis of ventricular mechanics in hypertrophic cardiomyopathy patients

Abstract Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is associated with many pathological features, such as a reduction in global longitudinal strain (GLS), myofiber disarray and hypertrophy. The effects of these features on left ventricle (LV) function are, however, not clear...

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Bibliographic Details
Main Authors: Joy Mojumder, Lei Fan, Thuy Nguyen, Kenneth S. Campbell, Jonathan F. Wenk, Julius M. Guccione, Theodore Abraham, Lik Chuan Lee
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28037-w