Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates

Chemo-select modification of peptides, targeting a handful of the most reactive proteinogenic amino acids (AAs), is gradually utilized to address the medical needs of peptide drugs and biopharmaceuticals. Cysteine (Cys), one of the less abundant AAs in many biological proteins, plays a vital role in...

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Hlavní autoři: Yanyan Liao, Xuefeng Jiang
Médium: Článek
Jazyk:English
Vydáno: Open Exploration 2024-09-01
Edice:Exploration of Drug Science
Témata:
On-line přístup:https://www.explorationpub.com/uploads/Article/A100860/100860.pdf