Ageing increases vulnerability to aβ42 toxicity in Drosophila.

Age is the major risk factor for many neurodegenerative diseases, including Alzheimer's Disease (AD), for reasons that are not clear. The association could indicate that the duration or degree of exposure to toxic proteins is important for pathology, or that age itself increases susceptibility...

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Bibliographic Details
Main Authors: Iain Rogers, Fiona Kerr, Pedro Martinez, John Hardy, Simon Lovestone, Linda Partridge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3395685?pdf=render