Uncovering a novel pathway for p16 silencing: Therapeutic implications for lung cancer

A key step during onset of most cases of non-small cell lung cancer (NSCLC) is the loss of the tumor suppressor p16INK4a (best known as p16), commonly due to promoter hypermethylation. We recently reported a novel regulatory pathway involving E6-associated protein and cell division control protein 6...

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Bibliographic Details
Main Authors: C. Gamell, T. Gulati, B. Solomon, S. Haupt, Y. Haupt
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2017.1299273