Design and Synthesis of new Naproxen Analogues as Potential Anti-inflammatory Agents
4-aminobenzenesulfonamide derivatives were linked to α-carbon of naproxen a non-selective non-steroidal anti-inflammatory drug (NSAID) to increase its size, so; increase its selectivity toward COX-2 enzyme, rather than COX-1 enzyme, that lead to reduce gastrointestinal side effects of this drug. Th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy / Mustansiriyah University
2018-03-01
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| Series: | Al-Mustansiriyah Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://ajps.uomustansiriyah.edu.iq/index.php/AJPS/article/view/61 |