Determining the Likelihood of Disease Pathogenicity Among Incidentally Identified Genetic Variants in Rare Dilated Cardiomyopathy‐Associated Genes

Determining the Likelihood of Disease Pathogenicity Among Incidentally Identified Genetic Variants in Rare Dilated Cardiomyopathy‐Associated Genes

Background As utilization of clinical exome sequencing (ES) has expanded, criteria for evaluating the diagnostic weight of incidentally identified variants are critical to guide clinicians and researchers. This is particularly important in genes associated with dilated cardiomyopathy (DCM), which ca...

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Bibliographic Details
Main Authors: Qixin Yang, Amy M. Berkman, Jordan E. Ezekian, Michael Rosamilia, Jill A. Rosenfeld, Pengfei Liu, Andrew P. Landstrom
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
dilated cardiomyopathy
exome sequencing
genetics
incidental finding
secondary finding
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.025257

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https://www.ahajournals.org/doi/10.1161/JAHA.122.025257

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