Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its limited aqueous solubility. The aim of this study was to develop glimepiride tablets using three different manufacturing techniques, as well as to study their quality attributes and pharmacokinetics behavio...

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Bibliographic Details
Main Authors: Tarek A. Ahmed, Hanadi A. Alotaibi, Waleed S. Alharbi, Martin K. Safo, Khalid M. El-Say
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceuticals
Subjects:
glimepiride
black seed oil
SNEDDS
three-dimensional printed tablets
liquisolid technique
direct compression
Online Access:https://www.mdpi.com/1424-8247/15/1/68

Internet

https://www.mdpi.com/1424-8247/15/1/68

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