New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

New Derivatives of 5-Substituted Uracils: Potential Agents with a Wide Spectrum of Biological Activity

Pyrimidine nucleoside analogues are widely used to treat infections caused by the human immunodeficiency virus (HIV) and DNA viruses from the herpes family. It has been shown that 5-substituted uracil derivatives can inhibit HIV-1, herpes family viruses, mycobacteria and other pathogens through vari...

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Bibliographic Details
Main Authors: Vasily A. Kezin, Elena S. Matyugina, Mikhail S. Novikov, Alexander O. Chizhov, Robert Snoeck, Graciela Andrei, Sergei N. Kochetkov, Anastasia L. Khandazhinskaya
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Molecules
Subjects:
5′-norcarbocyclic nucleoside analogues
chemical synthesis
RNA viruses
Online Access:https://www.mdpi.com/1420-3049/27/9/2866

Internet

https://www.mdpi.com/1420-3049/27/9/2866

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