Acetylation Enhances the Anticancer Activity and Oral Bioavailability of 5-Demethyltangeretin

Acetylation Enhances the Anticancer Activity and Oral Bioavailability of 5-Demethyltangeretin

A kind of hydroxylated polymethoxyflavone (PMFs) existing in the citrus genus, 5-Demethyltangeretin (5-DTAN), has been reported to possess several bioactivities in vitro and in vivo. The aim of this study was to investigate whether acetylation could enhance the anticancer activity and oral bioavaila...

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Bibliographic Details
Main Authors: Hui-Yun Tsai, Jia-Fang Yang, Yin-Bo Chen, Jia-Lin Guo, Shiming Li, Guor-Jien Wei, Chi-Tang Ho, Jue-Liang Hsu, Chi-I Chang, Yu-Shen Liang, Hsu-Sheng Yu, Yu-Kuo Chen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
anticancer
citrus
polymethoxyflavones
acetylation
bioavailability
Online Access:https://www.mdpi.com/1422-0067/23/21/13284

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https://www.mdpi.com/1422-0067/23/21/13284

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