A male-specific doublesex isoform reveals an evolutionary pathway of sexual development via distinct alternative splicing mechanisms

An ancestral male-specific doublesex isoform, dsxM2, is identified via intron retention, with a masculinizing function weaker than the modern dsxM

Bibliographic Details
Main Authors: Caihong Han, Qionglin Peng, Xiangbin Su, Limin Xing, Xiaoxiao Ji, Yufeng Pan
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03664-7