Low-dose lithium adjunct to atypical antipsychotic treatment nearly improved cognitive impairment, deteriorated the gray-matter volume, and decreased the interleukin-6 level in drug-naive patients with first schizophrenia symptoms: a follow-up pilot study

Abstract This study was conducted to investigate the effects of long-term low-dose lithium adjunct to antipsychotic agent use on the cognitive performance, whole-brain gray-matter volume (GMV), and interleukin-6 (IL-6) level in drug-naive patients with first-episode schizophrenia, and to examine rel...

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Bibliographic Details
Main Authors: Chuanjun Zhuo, Shuiqing Hu, Guangdong Chen, Lei Yang, Ziyao Cai, Hongjun Tian, Deguo Jiang, Chunmian Chen, Lina Wang, Xiaoyan Ma, Ranli Li
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-023-00400-w